“Paragon’s release represents years of technology development and validation work to move molecular profiling of cancer tissues out of the analog approaches that persist today, and into the digital world.” said Dr. Jarret Glasscock, Chief Executive Officer of Cofactor Genomics.
“The cancer immune cycle is complex, necessitating sensitive and robust RNA-based technologies to inform treatment decisions. Technologies like Cofactor Paragon will facilitate current drug development and fuel the future of precision medicine”
Cancer's Immune Cycle
immune cell + gene expression
solid tumor microenvironment profiling
Version: 1.1 Cofactor Genomics introduces Paragon, an RNA-based immune profiling assay which enables a unique look into an oncology patient’s immune profile – far beyond traditional “hot” or “cold” classification.
reports on 8 major cell types + expression of 10 key immune checkpoint molecules
with multidimensional biomarker analysis included
Clinical archives and samples such as FFPE, FNAs, CNBs, and LCM solid tumors have previously been difficult to characterize. Paragon accommodates these valuable and degraded materials with very low inputs and provides extensive immune characterization beyond current technologies – including differentiating cells such as M1 and M2 macrophages and Tregs – with high confidence. Find new biomarkers or improve patient selection as you transition from translational to clinical research applications.
Submit your samples to Cofactor and we’ll deliver a fully-analyzed data set highlighting immune escape genes and immune cell profiles, in one easy-to-interpret report. Don’t settle for qualitative, generic characterization from disparate assays such as IHC, flow cytometry, or expression arrays. Gain novel immune insights quickly and confidently.
Cofactor’s Paragon Assay is for Research Use Only and should not be used as a diagnostic assay.
CD4+ T cells, CD8+ T cells, CD19+ B cells, CD14+ Monocytes, CD56+ NK cells, M1 Macrophages, M2 Macrophages, Treg cells
PD-1, PD-L1, CTLA4, OX40, TIM-3, BTLA, ICOS, CD47, IDO1, ARG1
Don’t see your gene or immune marker of interest? Let us know.
Translational Immune Profiling Assays
|Product Name||Catalog Number||Description||Price per Sample|
|Paragon Assay||CFGDX-301||Individual immune report including gene expression for 8 cell types and 10 immune inhibitory molecules plus multidimensional biomarker report for sample cohorts||Contact Us|
|Contact [email protected] to learn more.|