Results you can act on.
Cofactor ImmunoPrism™ delivers improved tumor marker analysis and biological insights for immune-oncology using machine-learning based expression models.
By building our expression models from the ground up, we’ve created a new way of looking at biology — with greater resolution and depth than individual signatures or gene expression markers. These models are pathway agnostic and rely on the dynamic nature of RNA to define what makes a patient, cell type, or disease unique.
While most assays stop at the delivery of data, our ImmunoPrism™ assay provides actionable biomarkers that can predict responses to drug therapy and help you make critical clinical decisions.
Data from each patient cohort is analyzed using our proprietary Prism database of HEMs to provide an individual report summarizing the immune profile of each patient. Additionally, it generates a report which highlights biomarkers and the statistics that define each cohort.
Products Designed to Help You Make Informed Treatment Decisions
Receive the ImmunoPrism™ kit and use your own sequencing resources to gain access to the same technology utilized in our laboratories to derive your patients’ immune score. You’ll receive robust biomarkers and detailed insights in a fully-analyzed and easy-to-interpret report that eliminates the need for further bioinformatic or statistical analysis.
You can also choose to add on our user-friendly Extraction Kit optimized to provide the highest quality and quantity of total RNA from FFPE tissues for input into the ImmunoPrism™ assay.
|Product Name||Catalog Number||Description||List Price|
|ImmunoPrism Assay – RUO||CFGDX-301||Cofactor ImmunoPrism Assay – Research Use Only||$1,900|
|ImmunoPrism Assay – CAP||CFGDX-302||Cofactor ImmunoPrism Assay – Clinically-validated||$2,920|
|ImmunoPrism Kit – 8 reaction||CFGK-301||Cofactor ImmunoPrism Immune Profiling Kit – 8 reactions||$4,792|
|ImmunoPrism Kit – 24 reaction||CFGK-302||Cofactor ImmunoPrism Immune Profiling Kit – 24 reactions||$13,176|
|Prism Extraction Kit||CFGK-401||Cofactor Prism FFPE Extraction Kit – 24 samples||$250|
“Our database of Health Expression Models (HEMs) is providing insights beyond what was previously possible in the tumor microenvironment.”
– Dr. Jarret Glasscock, CEO
- Accepts RNA from all solid tumor types with inputs as low as 20 ng.
- Delivers fully-analyzed biomarker discovery report with quantitative immune cell characterization – enabling intra and inter sample comparisons.
- Unique biomarker analysis delivers most predictive markers in defined sample cohort (responders/non-responders, pre/post-treatment, stage, etc).
- Enables high-throughput analysis of TILs and escape genes from FFPE.
- Only 20 ng of RNA input required.
- As few as two FFPE sections required.
- Accepts all solid tumor tissues including fresh, frozen, FFPE or previously extracted RNA.
We’ve invested in optimizing workflows and building databases so you don’t have to. Receive a full biomarker analysis with quantitative characterization including statistics and multidimensional data that’s both cost-effective and time-sensitive.
We’ve got your most challenging samples covered, including all solid tumor types with inputs as low as 20 ng. Receive timely, reliable and precise data from scientists who are always on the verge of innovation. And get hands-on support from a team that’s focused on your needs.
Our signature molecular and analysis tools, paired with our HEMs database enables higher specificity of difficult-to-analyze cell types. So we can deliver more accurate, sensitive and actionable biomarker results.
ImmunoPrism Assay Report
Our ImmunoPrism™ assay reports on the most impactful immune modulatory molecules demonstrated to have implications in drug discovery, biomarker development, and immunotherapy efficacy monitoring.
Featured Immune Cells & Escape Genes
Immune Cells: CD4+ T cells, CD8+ T cells, CD19+ B cells, CD14+ Monocytes, CD56+ NK cells, M1 Macrophages, M2 Macrophages, Treg cells
Escape Genes: PD-1, PD-L1, CTLA4, OX40, TIM-3, BTLA, ICOS, CD47, IDO1, ARG1
Don’t see your gene or immune marker of interest?
ImmunoPrism Data Sheet
Download the Data Sheet with validation data and applications.
Access to Prism Portal
Ready to upload your data for analysis?
Find Robust Biomarkers
Discover Multidimensional Biomakers with powerful predictive accuracy.
The ImmunoPrism™ assay was developed and characterized by Cofactor Genomics in San Francisco, CA. ImmunoPrism™ reagents are for Research Use Only and not for use in diagnostics procedures. The results of the included report are generated by a specific ImmunoPrism™ Version and are subject to change in future releases. Gene expression levels of escape genes are calculated for the sample in comparison to mean expression across various cancers. Immune profiling in ImmunoPrism™ has been shown to significantly correlate with flow cytometry measurements for PBMC samples across 5 different immune cell types. In addition, ImmunoPrism™ immune profiling has also shown to be consistent across fresh-frozen and formalin-fixed samples. Furthermore, ImmunoPrism™ immune profiling has been validated in dissociated tumor cells. For technical support or additional information on assay performance or validation, please contact: [email protected].
Cofactor’s ImmunoPrism™ Assay is offered both for Research Use Only (not to be used as a diagnostic assay) and as a CAP-validated assay. Please contact us to discuss which option is right for your application.