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“Functional to FFPE”

T Cell Exhaustion Early-Access Grant Program

Predictive Immune Modeling enables Functional Assays in FFPE

At Cofactor Genomics, we are eager to get the latest technology into our customers’ hands and see the impact they will have on precision medicine. To address a current challenge in immune-oncology, Cofactor has developed an assay to evaluate exhaustion, activation, memory or unstimulated T Cell states in both cell therapy products and FFPE patient samples. We are pleased to announce our 2019 “Functional to FFPE” Early-Access Exhaustion Grant worth $100,000.


Imagine if you could easily measure T Cell state without the need for viable cells, laborious functional assays, or massive amounts of tissue! Cofactor’s multidimensional Health Expression Models of T Cell state have made this feasible – with minimal cells or tissues required. This T Cell State Profiling product can help cell therapy researchers characterize their cell therapy products at every stage, or help cancer researchers study the immune response in a solid tumor.

Exhaustion Grant
RNA models estimate and capture the change from unstimulated, to peak activation, to full exhaustion.

Want to apply for Cofactor Genomics, “Functional to FFPE” Early-Access Exhaustion Grant?

The successful applicant will receive access to Cofactor’s technical team and facilities to process a cohort of solid tumor or cell product materials with Cofactor’s Early Access T Cell State Profiling Technology. The grant includes reagents, sequencing, and bioinformatics using Cofactor’s internal resources. Interested? Apply here before December 20, 2019.

The process is simple.

Step 1: Check if you are eligible.
Are you 18+, a research scientist, with 2 peer reviewed publications in the last 2 years?

Step 2: Understand the selection criteria.
A Cofactor Genomics Advisory Committee will review the applications and select a successful applicant based on the following:

  1. Research objective aimed at leveraging the ability to measure exhaustion, activation, or memory T cell states – 30%
  2. Research plan meeting the sample requirements – 30%
  3. Research plan leveraging Cofactor’s technology – 20%
  4. Potential to generate data for publication within the year – 20%

Step 3: Know what to expect if you are the successful applicant.
We recommend that you read the Grant Terms and Conditions entirely.

Step 4: Draft your application, and submit below.
We recommend including the following details: 

  • Disease and treatment (if applicable) being studied
  • Number of available samples
  • What defines the cohorts that are being compared
  • Why you’d like to partner with Cofactor and any other relevant details you think may be important

Step 5: Await the results.
The winning applicant will be notified by email.

Submit your application by completing the form and uploading your abstract before 5:00 pm CT on Friday December 20, 2019.

Submit your application:

    First Name (required)

    Last Name (required)

    Email (required)

    Company or Institution (required)

    Phone Number

    Upload Your Application (No more than 800 words, Required)

    Frequently Asked Questions

    When will I know the result?

    The successful applicant for the research grant will be contacted by email by January 3, 2020.


    Can I apply for the grant if I am to relocate outside of the United States?

    Unfortunately, the grant will only be eligible for research conducted in the United States this year.


    Am I eligible to apply if I am not a United States citizen?

    Yes, applicants can be a resident of other countries, working for the duration of the project in the United States.


    Will Cofactor Genomics commercialize any discoveries resulting from the research conducted using this grant?

    No, Cofactor Genomics will only be granted rights to promote the utilization of results from the research for the marketing of Cofactor Genomics’ products.


    What type of samples are acceptable/required?

    FFPE, fresh frozen solid tumors, or cryopreserved cell pellets. Relevant clinical data for each sample should be included. A small pilot study will be conducted by Cofactor at no charge for the project selected for the grant to ensure that sample type, quality, and quantity are sufficient to proceed prior to initiating the full project. All samples must be available at the start of the project.


    Am I eligible to apply as a research employee of a private company?

    Yes, employees of private companies are eligible as well.


    May I apply for the grant multiple times with different projects?

    Yes, each individual may apply for the grant with several projects.


    Is the research grant only limited to projects on human research?

    Yes, the grant is limited to human research only.

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