Molecular Subtyping and Cancer
Cancer Molecular Subtypes Molecular subtyping refers to the use of -omics data to find clusters of tumors within a cancer type that have shared characteristics. Whereas earlier attempts to find [...]
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Cancer Molecular Subtypes Molecular subtyping refers to the use of -omics data to find clusters of tumors within a cancer type that have shared characteristics. Whereas earlier attempts to find [...]
By Tiange (Alex) Cui, Ph.D. The term ‘Machine Learning’ was coined in 1959 by Arthur Samuel, who defined it as — “The field of study that gives computers the ability to learn without being [...]
By Joey Babbitt The first thing to know about cancer is that “cancer” is not one disease. There are a hundred different forms of cancer caused by a multitude of biological processes that behave [...]
By Ian Schillebeeckx, PhD Predictive Immune Modeling is the discipline of using many facets of immune activity to predict clinical outcomes in research or in the clinic. Core to this discipline, [...]
By Brent Wilson, PhD Types of Trials A clinical trial can take many structures. A single-arm trial is perhaps the simplest, which measures a response to therapy over time. This may have several [...]
By Kevin Flanagan, PhD PD-1 and PD-L1 inhibitors have growing importance in cancer treatment. Many tumors express PD-L1, a cell surface protein that binds to PD-1. PD-1 is expressed by T cells, [...]
By Dave Messina As part of the Clinical Biomarkers & World CDx Conference held in Boston last month, I had the honor of moderating a panel on a fascinating and timely topic, [...]
In our last interview, we spoke with John Kuelper, Managing Director at Ascension Ventures. We’re continuing to speak to industry experts to get their perspective on what’s going on [...]
Dysfunctional T Cells Tumor Infiltrating Lymphocytes (TILs) are immune cells that exist in the tumor. In concept, these immune cells, particularly CD8+, work to detect the tumor and (most [...]
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